Research Mentors

Director, BIO5 Instituate

Professor, Biomedical Engineering

Research Interests:

Biomedical Optics, Optical Coherence, Tomography, Fluorescence, Spectroscopy, Tissue Optics, Colon Cancer, Ovarian Cancer

Professor, Pathology

Research Topic: 

Relationship between oxidative stress and disease processes, particularly cancer

Associate Professor, Immunology

Vice Chair, Cancer Biology Graduate Interdisciplinary Program

Research Topic: 

Biology of capsid structure, viral entry, trafficking, uncoating, membrane penetration, and the innate cellular responses to HPV viral infection

Associate Professor, Otolaryngology

Research Topic: Molecular mechanisms promoting the development of squamous cell carcinoma of the skin, head and neck

Associate Professor, Medicine

Research Topic:

Breast cancer and bleeding/clotting disorders

Associate Professor, Molecular and Cellular Biology

Research Topic:

Understanding the molecular basis of directed cell migration

Professor, Pharmacology

Research Topic: 

Molecular mechanisms of oxidative injury and adaptation, stress signal transduction pathways, stress gene expression, senescence, apoptosis and cardiac hypertrophy

Professor, Nutritional Sciences

Research Topic:

How genetic and epigenetic variations interact with human diets (especially the modern Western diet) to drive inflammation and inflammatory disorders (including cardiovascular disease and cancer), as well as psychiatric/developmental disorders (ADHD, autism spectrum disorder, and depression)

Research Professor, Medicine

Research Topic:

Early phase clinical development of cancer chemopreventive agents and development of biochemical and molecular biomarkers for evaluation of cancer risk and drug efficacy

Professor, Cellular & Molecular Medicine

Deputy Dean, Research Affairs, Coll. of Medicine

Research Topic:

Regulation of normal and cancer cell responses to environmental signals

Research Assistant Professor, Cellular & Molecular Medicine

Research Topic:

Single-cell genomic technologies

Professor, Molecular and Cellular Biology

Research Topic:

Organelle organization and function

Associate Professor, Cellular & Molecular Medicine

Research Topic:

Genomic instability, cancer susceptibility, genetic analysis of colorectal cancers

Associate Professor, Medicine

Research Topic:

Use of medicinal compounds for disease treatments such as breast cancer

Professor, Pharmacology & Toxicology

Research Topic:

Cancer epigenetics

Professor, Immunobiology

Research Topic:

Human cytomegalovirus (CMV) latency

Professor, Natural Resources & the Environment

Research Topic:

Natural products and medicinal chemistry including isolation, characterization and partial synthesis of anticancer agents and their mechanisms of action

Associate Professor, Molecular & Cellular Biology

Research Topic:

Computational systems biology and population genetics;  mathematical simulations of protein networks

Associate Professor, Basic Medical Sciences

Research Topic:

Antigen processing and immune recognition of melanoma

Professor, Surgery

Research Topic:

Molecular mechanisms of angiogenesis and prostate carcinoma epithelial-mesenchymal transformation; regulation of cadherins in vascular morphogenesis

Associate Professor, Cellular & Molecular Medicine

Research Topic:

Study of the molecular changes in gaA leading to malignancy for the purpose of identification of molecular markers for detection or prevention of gastrointestinal cancer

Professor, Pediatrics

Research Topic:

Mechanisms of tumor-induced immunosuppression; promotion of anti-tumor immunity

Associate Professor, Basic Medical Sciences

Research Topic:

Cancer biology and tumor suppressors

Professor, Medicine

Research Topic:

Genetic biomarkers in prostate cancer; The role of multiple protein kinases and signal transduction pathways in regulating tumor growth

Professor, Medical Imaging

Research Topic: 

Contrast agents, Molecular Imaging, PET, Nuclear Medicine, MR Imaging, Cancer, Neurology, Nephrogenic Systemic Fibrosis

Associate Professor, Medicine

Research Topic:

Gene copy number variation in cancer

Associate Professor, Pharmacology

Research Topic:

Cancer pharmacology/biology, cardiovascular pharmacology, molecular and biochemical pharmacology

Professor, Nutritional Sciences

Research Topic:

Radiation-induced salivary gland dysfunction; mechanisms of damage, clinical prevention measures, and restoration therapies

Associate Professor, Cellular & Molecular Medicine

Research Topic:

Relationship between epigenetic and genomic instability; regulation of transposable elements and repeat-gene clusters

Professor, Medicine

Research Topic:

Gastric cancer

Chair, Cancer Biology Graduate Interdisciplinary Program

Professor, Cellular and Molecular Medicine

Research Topic:

Prostate cancer, integrin interactions within the tumor microenvironment

Professor, Chemistry & Biochemistry

Research Topic:

Determine the atomic structures of proteins and seek to understand how protein structure gives rise to protein function - both in vitro and in living cells

Assistant Professor, Cellular and Molecular Medicine

Research Topic:

Invasion and metastasis of breast cancer through use of analytical cell biology and quantitative cellular microscopy

Associate Professor, Medicine

Research Topic:

Evaluation of the molecular mechanisms of action of novel experimental cancer therapeutics with an emphasis on targeting protein degradation and autophagy

Professor, Pathology

Research Topic:

Inflammation and tumor progression/metastasis; Racial disparities and cancer; Molecular diagnosis of cancer and other genetic diseases

Assistant Professor, Pharmacology and Toxicology

Research Topic:

Hereditary leiomyomatosis and renal cell cancer (HLRCC); Development of algorithms for the analysis of transcriptomic data; Transcriptional and metabolic reprogramming in response to physiochemical stimuli

Assistant Professor, Cellular and Molecular Medicine

Research Topic:

The Padi lab develops new computational approaches to integrate genomic “big data” and model how cellular networks are functionally altered by disease, genetic variation and epigenetics. Our ultimate goal is to identify drivers of disease, propose new therapeutic targets, and predict prognosis and drug response in a patient-specific manner.

Assistant Professor, Molecular & Cellular Biology

Research Topic:

The Paek Lab research focuses on understanding the heterogeneous response of cancer cells to chemotherapy treatment. The goal is to understand at the single cell level why some cells live while others die in response to treatment. 

Professor, Pharmacology

Research Topic:

Bone pain in cancer

Assistant Professor, Immunobiology

Research Topic:

Molecular remodeling of cellular metabolic and lipid environments by viruses

Associate Professor, Cellular and Molecular Medicine

Research Topic:

Regulation of centrosome duplication; Genomic instability and cancer

Professor, Nutritional Sciences

Research Topic:

Cellular and molecular mechanisms in mammary function; gene expression in cell proliferation and differentiation

Professor, Molecular and Cellular Biology

Research Topic:

Breast cancer progression and invasion

Associate Professor, Medicine

Research Topic:

Melanoma

Professor, Immunobiology

Research Topic:

Immunity in cancer and inflammatory diseases

Associate Professor, Medicine

Research Topic:

Clinical and translational research in gastrointestinal malignancies

Associate Professor, Nutritional Sciences

Research Topic:

The effects of exercise and stress on the immune system

Associate Professor, Pharmacology and Toxicology

Research Topic:

Epigenetic mechanisms of gene expression, particularly their regulation through signaling pathways and their modulation by anti-cancer drugs

Associate Professor, Pharmacology and Toxicology

Research Topic:

Angiogenesis; understanding the chemical and biological mechanisms of the antineoplastic, DNA-damaging natural product leinamycin; understanding inducible resistant mechanisms in human cancer cells to DNA-damaging anticancer drugs

Assistant Professor, Molecular and Cellular Biology

Research Topic:

Molecular basis of aging and age-related disease

Associate Director, Basic Sciences, University of Arizona Cancer Center

Director, University of Arizona Cancer Center

Research Topic:

Genomic instability and mutations that result in human diseases, such as cancer

Assistant Professor, Cellular and Molecular Medicine

Reseach Topic:

Intestinal stem cells, kinase networks, drug discovery

Associate Professor, Pharmacology and Toxicology

Research Topic:

The microenvironment of tumors is recognized as providing cancer cells with a selective advantage for growth.  Using HER2+ breast cancer cells, we have been investigating the role of lactate and the lactate receptor, GPR81, in regulating cancer cell growth.

Assistant Professor, Immunobiology

Research Topic:

My lab is interested in uncovering why, despite being genetically closely related, only a limited subset of human papillomaviruses is associated with human cancers. My research program leverages evolutionary  vidence to gain understanding of the complex, and medically relevant phenotypes. We use state-of-the-art molecular techniques including 3D (organotypic) skin models, genomics approaches, and confocal microscopy combined with thorough evolutionary analysis to address the genetic and molecular basis of tumorigenicity of HPV.

Assistant Professor, Cellular and Molecular Medicine

Research Topic:

Understanding the biological mechanisms that allow cancer cells to survive in the hypoxic tumor microenvironment, with a focus on developing novel strategies to oppose hypoxia-mediated therapeutic resistance

Professor, Molecular and Cellular Biology

Research Topic:

Genome instability in yeast and the mechanisms of genetic change

Assistant Professor, Immunobiology

Research Topic:

The Wilson lab's research focuses on understand how the dynamic relationship between innate immune sensors and the microbiota impacts chronic inflammation and cancer development at mucosal surfaces.

Professor, Cellular and Molecular Medicine

Research Topic:

Epithelial cells and neurons:regulation of development and polarity

Associate Professor, Pharmacology and Toxicology

Research Topic:

Development of novel molecular agents for skin cancer chemoprevention and chemotherapy

Associate Professor, Molecular and Cellular Biology

Research Topic:

Cancer pathways using quantitative systems biology

Professor, Cellular and Molecular Medicine

Research Topic:

Mechanisms that drive gastric epithelial regeneration and Helicobacter pylori-induced disease using in vitro and in vivo organoid systems

Professor, Pharmacology and Toxicology

Research Topic:

Nrf2/Keap1 signaling pathway