Hope Liou

PhD Student
Headshot of student, Hope Liou.
Pronouns:
she, her, hers

Research Advisor:

Noel Warfel

Research Topic:

Protein regulation; Autophagy regulation; Drug Development

Selected Publications:

Torres-Ayuso P, Katerji M, Mehlich D, Lookingbill SA, Sabbasani VR, Liou H, Casillas AL, Chauhan SS, Serwa R, Rubin MR, Marusiak AA, Swenson RE, Warfel NA, Brognard J. PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer. Cell Chem Biol. 2024 Feb 15;31(2):326-337.e11. doi: 10.1016/j.chembiol.2023.10.023. Epub 2023 Nov 27. PMID: 38016478.

Chauhan SS, Vizzerra AD, Liou H, Flores CE, Snider AJ, Snider JM, Warfel NA. Hypoxia-induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer. Oncotarget. 2025 Jun 25;16:532-544. doi: 10.18632/oncotarget.28750. PMID: 40560062; PMCID: PMC12196323.

Chauhan SS, Casillas AL, Vizzerra AD, Liou H, Clements AN, Flores CE, Prevost CT, Kashatus DF, Snider AJ, Snider JM, Warfel NA. PIM1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer. Oncogene. 2024 Feb;43(6):406-419. doi: 10.1038/s41388-023-02914-0. Epub 2023 Dec 14. PMID: 38097734; PMCID: PMC10837079

Blume JE, Manning WC, Troiano G, Hornburg D, Figa M, Hesterberg L, Platt TL, Zhao X, Cuaresma RA, Everley PA, Ko M, Liou H, Mahoney M, Ferdosi S, Elgierari EM, Stolarczyk C, Tangeysh B, Xia H, Benz R, Siddiqui A, Carr SA, Ma P, Langer R, Farias V, Farokhzad OC. Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona. Nat Commun. 2020 Jul 22;11(1):3662. doi: 10.1038/s41467-020-17033-7. PMID: 32699280; PMCID: PMC7376165.

Selected Presentations:

Defining PIM kinase protein regulation and PROTAC for pre-clinical testing, AACR San Diego, 2024

Degrees

  • University of Oregon, BS, Biology, 2017

Awards

  • Andrew C. Comrie Graduate Interdisciplinary Programs Doctoral Fellowship, University of Arizona, 2023
  • Cockrum Innovation Award, University of Arizona, 2023
  • Herbert E. Carter Travel Award, University of Arizona, 2024